Drug Discovery Seeds Development Unit

Discovering seed and lead compounds by HTS to develop new drugs

Unit Leader

Minoru Yoshida D.Agr.

1986: Ph.D., University of Tokyo
1986: Assistant Professor, University of Tokyo
1995: Associate Professor, University of Tokyo
2002: Chief Scientist, Chemical Genetics Laboratory, RIKEN
2002: Visiting Professor, University of Tokyo (-current)
2003: Visiting Professor, Saitama University (-current)
2008: Group Director, Chemical Genomics Research Group, RIKEN
2011: Visiting Professor, Kyoto University (-current)
2013: Group Director, Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science
2013: Division Director, Drug Discovery Platforms Cooperation Division, RIKEN Center for Sustainable Resource Science (-current)
2013: Unit Leader, Seed Compounds Exploratory Unit for Drug Discovery Platform, RIKEN Center for Sustainable Resource Science
2018: Unit Leader, Drug Discovery Seed Compounds Exploratory Unit, RIKEN Center for Sustainable Resource Science
2020: Deputy Director, RIKEN Center for Sustainable Resource Science
2025: Unit Leader, Drug Discovery Seeds Development Unit, RIKEN Center for Sustainable Resource Science (-current)

Main Research Fields :	Chemistry
Related Research Fields :	Biology
Keywords :	Chemical Biology / Epigenetics / Mode of Action / Transcriptional Regulation / Chemical Screening for Drug Discovery
Strategic Program :	Drug Discovery Platforms Cooperation Division

We aim to identify seed compounds for drug development, which are active on drug target molecules, through HTS of large compound libraries.

High throughput screening (HTS) using in vitro and cell-based assay systems
High content screening based on cell imaging
HTS for compounds that recover yeast phenotypes induced by expression of human genes

High throughput screening system in Seed Compounds Exploratory Unit for Drug Discovery Platform

Drug Discovery Platforms Cooperation Division,

yoshidam [at] riken.jp

WakoAccess

2-1 Hirosawa, Wako, Saitama 351-0198 Japan