Chemical Resource Development Research Unit
Expanding and using chemical libraries to accelerate chemical biology research
Unit Leader
Shinya Hagihara Ph.D.
- 2003
- Ph.D., Kyoto University
- 2003
- Postdoctoral fellow, Graduate School of Engineering, Kyoto University
- 2003
- Postdoctoral fellow, RIKEN
- 2007
- Postdoctoral fellow, Department of Organic Chemistry, University of Geneva, Switzerland
- 2008
- Assistant Professor, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University
- 2013
- Associate Professor, Institute of Transformative Bio-Molecules, Nagoya University
- 2015
- PRESTO Researcher
- 2016
- Associate Professor, Graduate School of Science, Nagoya University
- 2018
- Team Leader, Molecular Bioregulation Research Team, RIKEN Center for Sustainable Resource Science (-current)
- 2025
- Unit Leader, Chemical Resource Development Research Unit, RIKEN Center for Sustainable Resource Science (-current)
| Main Research Fields : | Complex Systems |
|---|---|
| Related Research Fields : | Informatics / Biological sciences / Agricultural sciences / Medicine, dentistry, and pharmacy |
| Keywords : | Chemical Biology / Natural Products Depository / Chembioinformatics / Chemical Library |
| Strategic Program : | Advanced Research and Technology Platforms  |
Outline
A chemical library is an indispensable tool to promote research on the regulation of cell functions and drug-discovery empowered by chemical biology. Our unit manages and enhances the NPDepo chemical library having the databases of its chemical and biological information. We explore useful bioactive compounds by our original phenotype- and target-based screening systems (iHOPE and chemical array), and elucidate mechanisms of action of hit compounds. We provide chemical libraries and their information to inside and outside RIKEN, promoting close collaborations with researchers in chemical biology and sustainable resource science.Subjects
- Expansion and utilization of chemical library in NPDepo
- Exploring of bioactive small molecules and their mode of action study
- Research promotion by structure-activity relationship analysis and optimization of chemical structures
- Profile of chemical library
CONTACT
Technology Platform Division,cb-secretary [at] riken.jp
