Development of technology for autonomous differentiation of transgenic plant cells

April 17, 2024

Contributing to saving labor for culturing cells and tissues

A research group at Chiba University, in collaboration with Nagoya University and the RIKEN CSRS, has developed technology for enabling transgenic cells to autonomously divide, grow, and differentiate into organs without applying external plant growth regulators (PGRs) such as hormones to media. The researchers introduced genes regulating cell division and morphogenesis into cells during plants’ developmental processes and had the genes expressed endogenously. They also identified the genes that change intracellular hormone levels and expression patterns. These findings could save labor for exploring conditions for applying appropriate PGRs to regulate plant cell differentiation and revolutionize current approaches that regulate differentiation by culture.

Original article

Frontiers in Plant Science doi: 10.3389/fpls.2024.1308417

Y. Sato, M. F. Minamikawa, B.B. Pratama S. Koyama, M. Kojima, Y. Takebayashi, H. Sakakibara, T. Igawa,

"Autonomous differentiation of transgenic cells requiring no external hormone application: the endogenous gene expression and phytohormone behaviors".

Contact

Mikiko Kojima
Expert Technician
Mass Spectrometry and Microscopy Unit