Chemical Biology and Biosynthesis Research Team
Production of novel bioactive compounds with biosynthetic ways
Team Director
Takayoshi Awakawa Ph.D. Agriculture
- 2011
- Ph.D in Agriculture, The University of Tokyo
- 2011
- Assistant Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- 2014
- University of California at San Diego, Scripps Institute of Oceanography Prof. Bradley Moore
- 2016
- Assistant Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- 2018
- Lecturer, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- 2019
- Associate Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
- 2022
- Team Director, Chemical Biology and Biosynthesis Research Team, RIKEN Center for Sustainable Resource Science (-current)
| Main Research Fields : | Complex systems |
|---|---|
| Related Research Fields : | Chemistry / Biology / Agricultural sciences / Medicine, dentistry, and pharmacy / Chemical Biology / Biomolecular Chemistry / Natural product chemistry |
| Keywords : | Chemical biology / Bioactive compounds / Synthetic biology / Biosynthetic redesign |
| Strategic Program : | Sustainable Bioproduction  Advanced Research and Technology Platforms  |
Outline
Our laboratory aims to contribute to solving social issues such as the decrease and depletion of natural resources and to advance environmental resource science research through research on chemical biology and biosynthesis, including research on new useful natural products using biosynthetic methods. We analyze the biosynthesis pathway of bioactive substances and construct substance production systems in microbial hosts. We create non-natural compounds by modifying biosynthetic pathways and enzyme functions in the production system. We also analyze the mechanism of action of the bioactive compounds and obtain new knowledge in chemical biology.Subjects
- Redesign of biosynthetic machinery
- Alteration of enzyme function
- Functional elucidation of bioactive compounds
CONTACT
takayoshi.awakawa [at] riken.jp
